In a follow-up to our article on THC vs CBD, we have created an infographic for all you visual learners out there! While only 2 of the many cannabinoids found in the cannabis plant, THC and CBD are amongst the most well studied and pertinent when considering whether or not you want to “get high” and/or relieve a variety of medical ailments.
THC vs CBD: A Summary
- Delta-9 tetrahydrocannabinol (THC) and cannabidiol (CBD), both active in marijuana, have different and sometimes opposite effects.
- CBD and THC both have the exact same molecular formula, but the atoms in each are assembled in different shapes, meaning they are “isomers”.
- THC is psychoactive and largely responsible for the marijuana high. CBD, however, is non-psychoactive.
- THC isolated in pharmaceuticals is useful as anti-nausea and anti-vomiting agent for cancer and AIDS patients, but CBD (or CBD-THC combination medications) appears to have a broader therapeutic potential.
- CBD has been shown to be effective in treating a wide range of conditions, including neurological disorders like epilepsy and some anxiety disorders, as well as post-traumatic stress syndrome in conjunction with THC.
- Both CBD and THC interact in different ways with the body’s own endocannabinoid system, mimicking specific neurotransmitters that help regulate everything from mood to appetite to sleep patterns and other crucial functions.
- As of mid-2017, CBD medication called Epidiolex was undergoing clinical trials for rare childhood seizure conditions.
- Synthetic THC medications in the form of Marinol (dronabinol) and Cesamet (nabilone) have been available for cancer and AIDS patients for decades, approved to prevent nausea and vomiting and increase appetite.
- THC and CBD have both been studied as anti-pain medications, especially for neuropathic pain which is difficult to control with traditional opioid treatments. Results about the effectiveness have been mixed, however.
- Sativex is a CBD-THC combination drug manufactured by the British company GW Pharmaceuticals. It has been tested for a number of different psychological and physical conditions, but it is not approved for use in the U.S.
- CBD and THC, along with the other cannabinoids and terpenes in whole marijuana, work to modulate each other’s effects in a phenomenon called the “entourage effect.” Scientists don’t yet understand exactly how this works.
THC vs CBD Infographic
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